2-Methyl-3-phenylacrolein
Names
[ CAS No. ]:
101-39-3
[ Name ]:
2-Methyl-3-phenylacrolein
[Synonym ]:
2-Propenal, 2-methyl-3-phenyl-, (2E)-
2-methyl-3-phenyl-2-propenal
Cinnamaldehyde, α-methyl-
α-Methylcinnamic aldehyde
3-Phenylmethacrolein
Cinnamaldehyde, α-methyl
α-Methyl-trans-cinnamaldehyde
(2E)-2-Methyl-3-phenylacrylaldehyde
EINECS 202-938-8
α-Methylcinnamaldehyde
2-methyl cinnamic aldehyde
alpha-Methylcinnamaldehyde
2-Methyl-3-phenylacrolein
MFCD00006976
3-Phenyl-2-methylacrolein
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
254.6±9.0 °C at 760 mmHg
[ Molecular Formula ]:
C10H10O
[ Molecular Weight ]:
146.186
[ Flash Point ]:
79.4±0.0 °C
[ Exact Mass ]:
146.073166
[ PSA ]:
17.07000
[ LogP ]:
2.68
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.563
[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents, strong bases.
[ Water Solubility ]:
<0.1 g/100 mL at 21 ºC
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GD6600000
- CHEMICAL NAME :
- Cinnamaldehyde, alpha-methyl-
- CAS REGISTRY NUMBER :
- 101-39-3
- BEILSTEIN REFERENCE NO. :
- 0507514
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C10-H10-O
- MOLECULAR WEIGHT :
- 146.20
- WISWESSER LINE NOTATION :
- VHYU1R
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - guinea pig
- REFERENCE :
- ADVEA4 Acta Dermato-Venereologica. (Almqvist & Wiksell, POB 45150, S-10430 Stockholm, Sweden) V.1- 1920- Volume(issue)/page/year: 58,121,1978 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2050 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 13,853,1975
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 13,853,1975 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - E0422 No. of Facilities: 2961 (estimated) No. of Industries: 28 No. of Occupations: 25 No. of Employees: 25103 (estimated) No. of Female Employees: 5134 (estimated)
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
R36/37/38:Irritating to eyes, respiratory system and skin .
[ Safety Phrases ]:
S24/25
[ WGK Germany ]:
1
[ RTECS ]:
GD6600000
[ HS Code ]:
2912299000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2912299000
[ Summary ]:
2912299000. other cyclic aldehydes without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%
Articles
Biometals 24(5) , 923-33, (2011)
Antifungal effectivity and utility of cinnamaldehyde is limited because of its high MIC and skin sensitivity. In this study, α-methyl trans cinnamaldehyde, a less irritating derivative, have been self...