SORT-PGRN interaction inhibitor 2

Names

[ CAS No. ]:
1008233-79-1

[ Name ]:
SORT-PGRN interaction inhibitor 2

Biological Activity

[Description]:

SORT-PGRN interaction inhibitor 2 is a SORT-PGRN inhibitor that can decreases SORT1 protein expression and increases extracellular PGRN secretion in mammalian cell lines. SORT-PGRN interaction inhibitor 2 can be used for neurological disease research[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[References]

[1]. Lee WC, et.al. Targeted manipulation of the sortilin-progranulin axis rescues progranulin haploinsufficiency. Hum Mol Genet. 2014 Mar 15;23(6):1467-78.  

Chemical & Physical Properties

[ Molecular Formula ]:
C19H31NO

[ Molecular Weight ]:
289.46

Related Compounds

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