Phenol,2-(1,3,4-oxadiazol-2-yl)-

Names

[ CAS No. ]:
1008-65-7

[ Name ]:
Phenol,2-(1,3,4-oxadiazol-2-yl)-

[Synonym ]:
MFCD00020713
2-(1,3,4-OXADIAZOL-2-YL)PHENOL

Biological Activity

[Description]:

Fenadiazole acts as a central nervous system agent to manage insomnia and dreaminess[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[References]

[1]. Huai-HeZhu, et al. Integration of naturally bioactive thiazolium and 1,3,4-oxadiazole fragments in a single molecular architecture as prospective antimicrobial surrogates.Journal of Saudi Chemical Society. 2020 Jan, 24 (1):127-138.

Chemical & Physical Properties

[ Density]:
1.38g/cm3

[ Boiling Point ]:
267.1ºC at 760mmHg

[ Melting Point ]:
108ºC

[ Molecular Formula ]:
C₈H₆N₂O₂

[ Molecular Weight ]:
162.14500

[ Flash Point ]:
115.3ºC

[ Exact Mass ]:
162.04300

[ PSA ]:
59.15000

[ LogP ]:
1.44220

[ Vapour Pressure ]:
0.00832mmHg at 25°C

[ Index of Refraction ]:
1.646

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SM5850000

CHEMICAL NAME :: Phenol, 2-(1,3,4-oxadiazol-2-yl)-

CAS REGISTRY NUMBER :: 1008-65-7

BEILSTEIN REFERENCE NO. :: 0136925

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C8-H6-N2-O2

MOLECULAR WEIGHT :: 162.16

WISWESSER LINE NOTATION :: T5NN DOJ CR BQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 940 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year: 11,620,1989

Safety Information

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

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