1-(2-Nitrobenzylidenamino)-2,4-imidazolidinedione-[2,4,5-13C]

Names

[ Name ]:
1-(2-Nitrobenzylidenamino)-2,4-imidazolidinedione-[2,4,5-13C]

[Synonym ]:
2-Np-Ahd-13C3

Biological Activity

[Description]:

2-NP-AHD-13C3 is the 13C labled 2-NP-AHD (HY-136457)[1]. 2-NP-AHD is a 2-nitrophenyl derivative of AHD (a metabolite of nitrofurans type of antibiotics), can be used as indicator of the illegal usage of nitrofuran agents[2].

[Related Catalog]:

Research Areas >> Others

[In Vitro]

氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.

Chemical & Physical Properties

[ Molecular Formula ]:
C₇₁₃C₃H₈N₄O₄

[ Molecular Weight ]:
251.17

[ Exact Mass ]:
251.06500

[ PSA ]:
111.08000

[ LogP ]:
1.21750

MSDS

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Safety Information

[ RIDADR ]:
NONH for all modes of transport