5-Methoxyindole

Names

[ Name ]:
5-Methoxyindole

[Synonym ]:
5-Methoxyindole
5-Methoxy indole
5-Methoxy-1H-indole
5-methoxy-indole
Methoxyindole
5-MeO-indole
EINECS 213-745-3
5-methoxy-indol
5-methoxy-2,3-dihydro-1H-indole
1H-Indole, 5-methoxy-
5-Methoxylindole
5-OMe-indole
Femedol
methoxy-5indole
MFCD00005674

Biological Activity

[Description]:

5-Methoxyindole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
311.9±0.0 °C at 760 mmHg

[ Melting Point ]:
52-55 °C(lit.)

[ Molecular Formula ]:
C₉H₉NO

[ Molecular Weight ]:
147.17

[ Flash Point ]:
109.2±10.1 °C

[ Exact Mass ]:
147.068420

[ PSA ]:
25.02000

[ LogP ]:
2.06

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.637

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
insoluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NL9500000

CHEMICAL NAME :: Indole, 5-methoxy-

CAS REGISTRY NUMBER :: 1006-94-6

LAST UPDATED :: 199109

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C9-H9-N-O

MOLECULAR WEIGHT :: 147.19

WISWESSER LINE NOTATION :: T56 BMJ GO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 370 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 9,453,1974

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S24/25-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
NL9500000

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Prediction of Setschenow constants of N-heteroaromatics in NaCl solutions based on the partial charge on the heterocyclic nitrogen atom.

Environ. Sci. Pollut. Res. Int. 23 , 3399-405, (2016)

The solubilities of 19 different kinds of N-heteroaromatic compounds in aqueous solutions with different concentrations of NaCl were determined at 298.15 K with a UV-vis spectrophotometry and titratio...

Assessment of the pharmacological properties of 5-methoxyindole derivatives at 5-HT4 receptors.

J. Pharm. Pharmacol. 64(8) , 1099-106, (2012)

The aim was to examine the biological activity of 5-methoxytryptamine derivatives at the 5-hydroxytryptamine (5-HT)(4) receptor to explore the effect of substitution on the aliphatic amine of the 5-me...

Rotationally resolved electronic spectroscopy of 5-methoxyindole.

J. Chem. Phys. 133(2) , 024303, (2010)

Rotationally resolved electronic spectra of the vibrationless origin and of eight vibronic bands of 5-methoxyindole (5MOI) have been measured and analyzed using an evolutionary strategy approach. The ...