nicotinamide chloromethylate
Names
[ CAS No. ]:
1005-24-9
[ Name ]:
nicotinamide chloromethylate
[Synonym ]:
N-methyl-3-carboxamidepyridinium chloride
nicotinamidemethochloride
n-methylnicotinic acid amide chloride
1-METHYLNICOTINAMIDE CHLORIDE
nicotinamide chloromethylate
MFCD00060042
Pyridinium, 3-(aminocarbonyl)-1-methyl-, chloride (1:1)
3-(Aminocarbonyl)-1-methylpyridinium Chloride
n-methylnicotinamidechloride
nicotinamidemethylchloride
1-METHYLNICOTINAMIDE CHLORIDE SALT
N1-Methylnicotinamide Chloride
EINECS 463-670-7
N-methyl-3-carbamoylpyridinium chloride
1-methyl-3-carbamoylpyridinium chloride
3-Carbamyl-1-methylpyridinium Chloride
3-Carbamoyl-1-methylpyridinium chloride
TRIGONELLAMIDE CHLORIDE
nipecotamidemethochloride
Chemical & Physical Properties
[ Melting Point ]:
207-209℃ (water acetone )
[ Molecular Formula ]:
C7H9ClN2O
[ Molecular Weight ]:
172.612
[ Exact Mass ]:
172.040344
[ PSA ]:
46.97000
[ Appearance of Characters ]:
crystalline | white
[ Storage condition ]:
room temp
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UU1925000
- CHEMICAL NAME :
- Pyridinium, 3-(aminocarbonyl)-1-methyl-, chloride
- CAS REGISTRY NUMBER :
- 1005-24-9
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C7-H9-N2-O.Cl
- MOLECULAR WEIGHT :
- 172.63
- WISWESSER LINE NOTATION :
- T6KJ A1 CVZ &Q &G
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2400 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 62,19,1946
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
UU1925000
[ HS Code ]:
2933399090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933399090
[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Clin. Biochem. 44(4) , 293-9, (2011)
We sought to identify metabolic pathways characterizing human heart failure (HF) using ¹NMR based urinary metabolomic analysis in conjunction with multivariate statistics.Patients with systolic HF of ...
Nicotinamide supplementation induces detrimental metabolic and epigenetic changes in developing rats.Br. J. Nutr. 110(12) , 2156-64, (2013)
Ecological evidence suggests that niacin (nicotinamide and nicotinic acid) fortification may be involved in the increased prevalence of obesity and type 2 diabetes, both of which are associated with i...
Single bout of endurance exercise increases NNMT activity in the liver and MNA concentration in plasma; the role of IL-6.Pharmacol. Rep. 64(2) , 369-76, (2012)
Methylnicotinamide (MNA) displays vasoprotective activity, however, the regulation of the activity of nicotinamide-N-methyltransferase (NNMT), is largely unknown. We analyze a possible involvement of ...