(D-Arg2)-Dermorphin (1-4) amide trifluoroacetate salt

Names

[ CAS No. ]:
100304-60-7

[ Name ]:
(D-Arg2)-Dermorphin (1-4) amide trifluoroacetate salt

[Synonym ]:
tyr-DArg-Phe-Gly-NH2
Tyr-D-Arg-Phe-Gly-NH2
(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-5-guanidino-pentanoic acid [(S)-1-(carbamoylmethyl-carbamoyl)-2-phenyl-ethyl]-amide

Biological Activity

[Description]:

[D-Arg2]Dermorphin-(1-4) amide is a N-terminal shorter peptide amide of [D-Arg2]dermorphin with the hypothermic effect. [D-Arg2]Dermorphin-(1-4) amide shows analgesic activity and degradation in soluble mouse liver and brain extracts[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[References]

[1]. Emel'ianova TG, et al. Termoreguliatornaia aktivnost' dermofinov [Thermoregulatory activity of dermorphin fragments]. Izv Akad Nauk Ser Biol. 2004 Sep-Oct;(5):570-6.  

Chemical & Physical Properties

[ Molecular Formula ]:
C26H36N8O5

[ Molecular Weight ]:
540.61500

[ Exact Mass ]:
540.28100

[ PSA ]:
238.54000

[ LogP ]:
2.10330