GnRH Associated Peptide: GAP: 1-13, human

Names

[ Name ]:
GnRH Associated Peptide: GAP: 1-13, human

[Synonym ]:
Gn-RH Associated Peptide (GAP) (1-13),human
GNRH ASSOCIATED PEPTIDE (1-13),HUMAN
Asp-Al-Glu-Asn-Leu-Ile-Asp-Ser-Phe-Gln-Glu-Ile-Val
GNRH precursor (14-26)
GAP (1-13) (HUMAN)
PREPRO HUMAN GNRH PRECURSOR PEPTIDE (14-26)
GAP (1-13)
GNRH PRECURSOR PEPTIDE (14-26) (HUMAN)
GNRH PRECURSOR (14-26),RAT
asp-ala-glu-asn-leu-ile-asp-ser-phe-*gln-glu-ile

Biological Activity

[Description]:

GnRH Associated Peptide (GAP) (1-13), human is an amino acid peptide fragment derived from GnRH. GAP can increase the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) in rat anterior pituitary cells. GAP also inhibit the secretion of prolactin[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> GNRH Receptor

Research Areas >> Endocrinology

[Target]

LH, FSH, Prolactin[1]

Chemical & Physical Properties

[ Molecular Formula ]:
C₆₅H₁₀₁N₁₅O₂₅

[ Molecular Weight ]:
1492.58000

[ Exact Mass ]:
1491.71000

[ PSA ]:
668.13000

[ LogP ]:
0.87670

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Stimulation of gonadotropin release by a non-GnRH peptide sequence of the GnRH precursor.

Science 232 , 68, (1986)

The human gonadotropin-releasing hormone (GnRH) precursor comprises the GnRH sequence followed by an extension of 59 amino acids. Basic amino acid residues in the carboxyl terminal extension may repre...

LH-releasing activity and receptor binding of pHGnRH 14-26 analogues.

Biochem. Biophys. Res. Commun. 143(3) , 872-9, (1987)

The human gonadotropin-releasing hormone (GnRH) precursor consists of the GnRH sequence followed by a cleavage and amidation site and a 56-amino acid carboxyl-terminal extension (pHGnRH - precursor hu...

Related Compounds

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