Gastric Inhibitory Polypeptide (human)

Names

[ CAS No. ]:
100040-31-1

[ Name ]:
Gastric Inhibitory Polypeptide (human)

[Synonym ]:
MFCD00081634
GIP, human
YAEGTFISDYSIAMDKIHQQDFVNWLLAQKGKKNDWKHNITQ
Gastric Inhibitory Peptide (GIP), human

Biological Activity

[Description]:

Gastric Inhibitory Peptide (GIP), human is thought to act as an inhibitor of gastric functions.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

Natural Products >> Others

Peptides

[In Vitro]

Gastric Inhibitory Polypeptide (GIP) exerts various peripheral effects on adipose tissue and lipid metabolism, thereby leading to increased lipid deposition in the postprandial state,sup>[1].

[References]

[1]. Meier JJ, et al. Gastric inhibitory polypeptide: the neglected incretin revisited. Regul Pept. 2002 Jul 15;107(1-3):1-13.

[Related Small Molecules]

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂₆H₃₃₈N₆₀O₆₆S

[ Molecular Weight ]:
4983.53

[ Storage condition ]:
-20°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3.0

Articles

Long-term persistence of hormonal adaptations to weight loss.

N. Engl. J. Med. 365 , 1597-1604, (2011)

After weight loss, changes in the circulating levels of several peripheral hormones involved in the homeostatic regulation of body weight occur. Whether these changes are transient or persist over tim...

Pleiotropic effects of GIP on islet function involve osteopontin.

Diabetes 60 , 2424-2433, (2011)

The incretin hormone GIP (glucose-dependent insulinotropic polypeptide) promotes pancreatic β-cell function by potentiating insulin secretion and β-cell proliferation. Recently, a combined analysis of...

Gastric inhibitory polypeptide and its receptor are expressed in the central nervous system and support neuronal survival.

Cent. Nerv. Syst. Agents Med. Chem. 11 , 210-222, (2011)

The development of neuronal apoptosis depends on an intrinsic transcriptional program. By DNA microarray technology, we have previously implicated a number of genes in different paradigms of neuronal ...

Related Compounds

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