Palladium-catalyzed synthesis of natural and unnatural 2-, 5-, and 7-oxygenated carbazole alkaloids from N-arylcyclohexane enaminones
R Bautista, PA Montoya, A Rebollar, E Burgueño…
Index: Bautista, Rafael; Montoya, Pablo A.; Rebollar, Araceli; Burgueno, Eleuterio; Tamariz, Joaquin Molecules, 2013 , vol. 18, # 9 p. 10334 - 10351
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Abstract
Abstract: A palladium-catalyzed synthesis of the carbazole framework is described, including the preparation of 2-, 5-, and 7-oxygenated natural and unnatural carbazole alkaloids. A series of N-arylcyclohexane enaminones, generated by condensation of cyclohexane-1, 3- dione with diverse anilines, were aromatized by a Pd (0)-catalyzed thermal treatment to afford the corresponding diarylamines. The latter were submitted to a Pd (II)-catalyzed ...
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