A semi-molten mixture of hexadecyltributylphosphonium bromide and potassium fluoride in the synthesis of organofluorine compounds
PS Bhadury, SK Raza, DK Jaiswal
Index: Bhadury, Pinaki S.; Raza, Syed K.; Jaiswal, Devendra K. Journal of Fluorine Chemistry, 1999 , vol. 99, # 2 p. 115 - 117
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Citation Number: 6
Abstract
A facile and effective reagent system comprising of a semi-molten mixture of hexadecyltributylphosphonium bromide and potassium fluoride has been developed and its scope has been investigated in nucleophilic fluoride exchange with various organohalides. This simple and convenient reagent system provides organofluorine compounds in high yields even with haloesters in which fluoride catalysed elimination is also feasible.
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