Preparation of. alpha.-fluorocarboxylic acids and derivatives

ST Purrington, DL Woodard

Index: Purrington, Suzanne T.; Woodard, Daniel L. Journal of Organic Chemistry, 1990 , vol. 55, # 10 p. 3423 - 3424

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Citation Number: 23

Abstract

Incorporation of fluorine in organic molecules leads to changes in chemical and physical properties that yield products which have applications in many fields. Of particular interest is the ability of fluorine to modify the reactivity of biologically active molecules.'a-Fluoro carbonyl derivatives2 are of importance in themselves and can also be used as building blocks to synthesize more complex molecule^.^ a-Fluoro carboxylate esters are often ...