An efficient synthesis of 2-quinoxalinecarboxylic acid

AE Harms

Index: Harms, Arthur E. Organic Process Research and Development, 2004 , vol. 8, # 4 p. 666 - 669

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Citation Number: 11

Abstract

Development of a cost efficient and scaleable process for 2-quinoxalinecarboxylic acid is described. The primarily goals of the development work were to improve the overall yield of the process, to minimize the use of environmentally unacceptable materials, and to obtain a material with a high level of purity. A variety of approaches were examined, and the most efficient method was a condensation of o-phenylenediamine with a monosaccharide ...