A mild method for the protection of alcohols using a para-methoxybenzylthio tetrazole (PMB-ST) under dual acid–base activation
SR Kotturi, JS Tan, MJ Lear
Index: Kotturi, Santosh R.; Tan, Jason S.; Lear, Martin J. Tetrahedron Letters, 2009 , vol. 50, # 37 p. 5267 - 5269
Full Text: HTML
Citation Number: 6
Abstract
With a view to expand the repertoire of chemoselective methods applicable to sensitive and multifunctional substrates, the p-methoxybenzylation of alcohols under essentially neutral conditions is reported. This was achieved by the silver triflate (AgOTf) activation of 5-(p- methoxybenzylthio)-1-phenyl-1H-tetrazole (PMB-ST) in the presence of 2, 6-di-tert-butyl-4- methylpyridine (DTBMP).
Related Articles:
[Zolfigol, Mohammad Ali; Mohammadpoor-Baltork, Iraj; Mirjalili, Bibi Fatemeh; Bamoniri, Abdolhamid Synlett, 2003 , # 12 p. 1877 - 1879]
[Yadav; Subba Reddy; Shiva Shankar; Swamy Tetrahedron Letters, 2010 , vol. 51, # 1 p. 46 - 48]
[Badri, Rashid; Kiasat, Ali Reza; Nazari, Simin Phosphorus, Sulfur and Silicon and the Related Elements, 2007 , vol. 182, # 3 p. 589 - 593]
Synthesis of para-methoxybenzyl (PMB) ethers under neutral conditions
[Nwoye, Ernest O.; Dudley, Gregory B. Chemical Communications, 2007 , # 14 p. 1436 - 1437]
Synthesis of para-methoxybenzyl (PMB) ethers under neutral conditions
[Nwoye, Ernest O.; Dudley, Gregory B. Chemical Communications, 2007 , # 14 p. 1436 - 1437]