Tetrahedron Letters

The reductive etherification of carbonyl compounds using polymethylhydrosiloxane activated by molecular iodine

JS Yadav, BVS Reddy, KS Shankar, T Swamy

Index: Yadav; Subba Reddy; Shiva Shankar; Swamy Tetrahedron Letters, 2010 , vol. 51, # 1 p. 46 - 48

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Citation Number: 17

Abstract

Aldehydes and ketones undergo a smooth reductive etherification by polymethylhydrosiloxane (PMHS) in the presence of a catalytic amount of molecular iodine under mild conditions to afford the corresponding symmetrical ethers in excellent yields. This new reagent system (PMHS/I2) provides a simple and convenient route for the preparation of symmetrical ethers from carbonyl compounds.