Metal chloride hydrates as Lewis acid catalysts in multicomponent synthesis of 2, 4, 5-triarylimidazoles or 2, 4, 5-triaryloxazoles

…, MM Ruthner, LAM Fontoura, D Russowsky

Index: Marques, Marcelo V.; Ruthner, Marcelo M.; Fontoura, Luiz A. M.; Russowsky, Dennis Journal of the Brazilian Chemical Society, 2012 , vol. 23, # 1 p. 171 - 179

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Citation Number: 26

Abstract

ABSTRACT A series of nine metal chloride hydrates (ZnCl 2. 2H 2 O, SnCl 2. 2H 2 O, CdCl 2. 2H 2 O, MnCl 2. 4H 2 O, CoCl 2. 6H 2 O, SrCl 2. 6H 2 O, NiCl 2. 6H 2 O, CrCl 3. 6H 2 O and CeCl 3. 7H 2 O) was investigated as mild and inexpensive Lewis acid catalysts to promote the multicomponent synthesis of triarylimidazoles. Reactions starting from benzil showed the best results when SnCl 2. 2H 2 O was used, while for benzoin as the starting ...

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