Microwave-assisted synthesis of some novel and potent antibacterial and antifungal compounds with biological screening

…, B Parashar, VK Sharma, LS Chouhan

Index: Bapna, Mayank; Parashar, Bharat; Sharma, Vinod K.; Chouhan, Lalit S. Medicinal Chemistry Research, 2012 , vol. 21, # 7 p. 1098 - 1106

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Citation Number: 4

Abstract

Abstract Hydantoins have widely been used as antiarrythmic, anticonvulsant and antitumor agents but recent research has shown a different and novel cytotoxic activity of hydantoins and its derivatives, ie anti HIV, antibacterial and antifungal. The following research article deals with the synthesis of hydantoins and their derivatives by Mannich reaction viz., 3- (substituted)-5, 5-diphenylimidazolidine-2, 4-dione and 1-(substituted)-3, 5, 5- ...