Hydantoin, 5,5-diphenyl-3-((4-methylpiperazinyl)methyl)-

DATA ITEMS CITED :

1

MOLECULAR FORMULA :

C21-H24-N4-O2

MOLECULAR WEIGHT :

364.49

WISWESSER LINE NOTATION :

T6N DNTJ A1 D1- CT5MVNV EHJ ER& ER

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

125 mg/kg

TOXIC EFFECTS :

Behavioral - convulsions or effect on seizure threshold Behavioral - excitement Lungs, Thorax, or Respiration - respiratory stimulation

REFERENCE :

DPHFAK Dissertationes Pharmaceuticae et Pharmacologicae. (Warsaw, Poland) V.18-24, 1966-72. For publisher information, see PJPPAA. Volume(issue)/page/year: 22,209,1970