Alkylation of Carbonyl Compounds in Water: Formation of C C and C O Bonds in the Presence of Surfactants

…, S Cerritelli, M Chiarini, P De Maria…

Index: Cerichelli, Giorgio; Cerritelli, Simona; Chiarini, Marco; De Maria, Paolo; Fontana, Antonella Chemistry - A European Journal, 2002 , vol. 8, # 22 p. 5204 - 5210

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Citation Number: 18

Abstract

Abstract The formation of C [BOND] C and C [BOND] O bonds by the reaction of enolate intermediates with electrophilic substrates commonly requires strong bases, aprotic solvents and very low temperatures. A way of performing the same reactions with sodium hydroxide at moderate temperatures in aqueous surfactant solutions is presented. Different halides, ketones and surfactants (cationic, zwitterionic and anionic) have been used. The results ...

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