Journal of the American Chemical Society

Some Variations of the Grignard Synthesis of Phosphinic Acids

GM Kosolapoff

Index: Kosolapoff Journal of the American Chemical Society, 1950 , vol. 72, p. 5508

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Citation Number: 21

Abstract

Several useful methods are available for the synthesis of phosphinic acids via the Grignard reagents. Thus, although the addition of phosphorus oxychloride to a Grignard reagent leads to the formation of a tertiary phosphine oxide it has been shown that the reversed order of addition employing dilute solutions is capable of limiting the reaction of disubstitution to the extent of about SO%, thus permitting the isolation after conventional ...

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