Photodermatology, Photoimmunology and Photomedicine 1996-12-01

Photoaugmentation effects demonstrated in vitro.

E Selvaag

Index: Photodermatol. Photoimmunol. Photomed. 12(6) , 227-32, (1996)

Full Text: HTML

Abstract

A number of sulphonamide-derived oral antidiabetics and diuretics were investigated for phototoxic properties, using different sources of light, by means of a photohemolysis test. Photohemolysis was obtained after irradiation with UVA, visible light and solar simulating irradiation. No phototoxic properties were seen when the test samples were exposed to UVB alone. The most prominent hemolysis was induced by solar simulating irradiation. When exposing the the test samples to UVB prior to the subsequently applied UVA, visible light or solar simulating irradiation, a significantly higher hemolysis was detected compared with the previous tests, suggesting photoaugmentation effects in this model.

Related Compounds

Related Articles:

Do thiazides reduce intestinal oxalate absorption?: a study in vitro using rabbit colon.

1994-03-01

[Clin. Sci. 86(3) , 353-7, (1994)]

Comparative effects of LN 5330 and diazoxide on insulin release and 86Rb+ permeability in perifused rat islets of Langerhans.

1991-07-25

[Biochem. Pharmacol. 42(4) , 787-91, (1991)]

Metabolic effects of propranolol and hydroflumethiazide treatment in Kenyans with mild to moderate essential hypertension.

1993-11-01

[East Afr. Med. J. 70(11) , 696-700, (1993)]

Phototoxicity to sulphonamide-derived oral antidiabetics and diuretics: investigations in hairless mice.

1997-01-01

[Photodermatol. Photoimmunol. Photomed. 13(1-2) , 4-8, (1997)]

Rapid determination of losartan and losartan acid in human plasma by multiplexed LC-MS/MS.

2009-10-01

[J. Sep. Sci. 32(20) , 3388-94, (2009)]

More Articles...