Design and synthesis of pyridine-substituted itraconazole analogues with improved antifungal activities, water solubility and bioavailability

Y Liu, Z Liu, X Cao, X Liu, H He, Y Yang

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 16 p. 4779 - 4783

Full Text: HTML

Citation Number: 10

Abstract

... Please enable JavaScript to use all the features on this page. Bioorganic & Medicinal Chemistry Letters. ... There is thus a great medical need for an injectable antifungal agent with a broad spectrum for the treatment of severe mycoses infections. ...

Related Articles:

Discovery of orally active carboxylic acid derivatives of 2-phenyl-5-trifluoromethyloxazole-4-carboxamide as potent diacylglycerol acyltransferase-1 inhibitors for the …

[Journal of Medicinal Chemistry, , vol. 54, # 7 p. 2433 - 2446]

Discovery of orally active carboxylic acid derivatives of 2-phenyl-5-trifluoromethyloxazole-4-carboxamide as potent diacylglycerol acyltransferase-1 inhibitors for the …

[Journal of Medicinal Chemistry, , vol. 54, # 7 p. 2433 - 2446]

Synthesis and solid state study of pyridine-and pyrimidine-based fragment libraries

[Tetrahedron Letters, , vol. 52, # 45 p. 5905 - 5909]

More Articles...