A novel synthesis and herbicidal activity of fluorine-containing pyrazolo [3, 4-d] pyrimidin-4-one derivatives

H Liu, HQ Wang, MW Ding, ZJ Liu, WJ Xiao

Index: Liu, Hui; Wang, Hong-Qing; Ding, Ming-Wu; Liu, Zhao-Jie; Xiao, Wen-Jing Journal of Fluorine Chemistry, 2006 , vol. 127, # 12 p. 1584 - 1590

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Citation Number: 17

Abstract

The 6-(4-alkoxycarbonylalkoxy) phenoxy-3-alkylthio-5-(fluoro-substituted) phenyl-1- phenylpyrazolo [3, 4-d] pyrimidin-4-ones 6 have been successfully synthesized via a tandem aza-Wittig and annulation reactions of the corresponding iminophosphorances 4, aromatic isocyanate, and substituted phenols 2 in 59–69% isolated yields using actonitrile as solvent. These novel compounds 6 could be oxidized to sulfones 7 by hydrogen peroxide in ...