Resolution of (R, S)-ethyl-2-(4-hydroxyphenoxy) propanoate using lyophilized mycelium of Aspergillus oryzae WZ007

JY Zheng, JY Wu, YJ Zhang, Z Wang

Index: Zheng, Jian-Yong; Wu, Jia-Yu; Zhang, Yin-Jun; Wang, Zhao Journal of Molecular Catalysis B: Enzymatic, 2013 , vol. 97, p. 62 - 66

Full Text: HTML

Citation Number: 1

Abstract

Abstract The mycelium of Aspergillus oryzae WZ007 was successfully developed to kinetic resolution of (R, S)-ethyl-2-(4-hydroxyphenoxy) propanoate ((R, S)-EHPP) for production of (R)-ethyl-2-(4-hydroxyphenoxy) propanoate ((R)-EHPP). The key biocatalytic process parameters (pH, temperature, rotation speed and substrate concentration) were optimized. Under the optimum conditions, the optical purity of (R)-EHPP was improved up to> 99% ...