Organic Letters
2003-07-01
Generation of aza-ortho-xylylenes via ring opening of 2-(2-acylaminophenyl)aziridines: application in the construction of the communesin ring system.
M Todd Washington, Sandra A Helquist, Eric T Kool, Louise Prakash, Satya Prakash
Index: Org. Lett. 8 , 3995, (2006)
Full Text: HTML
Abstract
A new protocol for generating aza-ortho-xylylenes via acid-catalyzed or fluoride-promoted ring opening of 2-(2-acylaminophenyl)aziridines is described. This methodology has been exploited in the rapid construction of a hexacyclic substructure of communesin B.
Related Compounds
Related Articles:
1985-09-01
[J. Med. Chem. 28(9) , 1309-13, (1985)]
Silicon compounds as substrates and inhibitors of acetylcholinesterase.
1984-12-07
[Biochim. Biophys. Acta 791(2) , 278-80, (1984)]
[J. Chem. Soc. Perkin Trans. I , 2639, (1993)]
[J. Org. Chem. 59 , 6687, (1994)]
[Tetrahedron Lett. 35 , 757, (1994)]