Alkylation of active methylene compounds with alcohols catalyzed by an iridium complex.
Masao Morita, Yasushi Obora, Yasutaka Ishii
Index: Chem. Commun. (Camb.) , 2850, (2007)
Full Text: HTML
Abstract
Base-free catalytic alpha-alkylation of active methylene compounds with primary alcohols was successfully achieved using an [IrCl(cod)](2) complex in the presence of PPh(3) to afford the corresponding saturated alpha-alkylated products in good yields.
Related Compounds
Related Articles:
A structure-based library approach to kinase inhibitors. Norman TC, et al.
[J. Am. Chem. Soc. 118(31) , 7430-31, (1996)]
Poly (benzyloxy ethyl methacrylate): preparation by free radical polymerization and by group transfer polymerization; with subsequent debenzylation to form poly (2-hydroxyethyl methacrylate). Dyakonov TA, et al.
[Eur. Polymer J. 36(9) , 1779-93, (2000)]