The Synthesis of β-Diketones Containing Chlorodifluoromethyl and Perfluoroethyl Groups and Certain Related Reactions1

RA Moore, R Levine

Index: Moore,R.A.; Levine,R. Journal of Organic Chemistry, 1964 , vol. 29, p. 1439 - 1444

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Citation Number: 35

Abstract

A series of p-diketones of the type RCOCH&OR', where R= CFzCl and C2F5, and R'= alkyl, aryl, and heterocyclic, has been prepared in high yields by the sodium methoxide-effected acylation8 of the appropriate ketones with methyl chlorodifluoroacetate and methyl pentafluoropropionate. While CFzClCOCHa (I) and CzF5COCH3 (VII) may be acylated under basic conditions with the very reactive esters methyl chlorodifluoroacetate and ...