Journal of Chromatography B 2012-06-01

A determinative and confirmatory method for ceftiofur metabolite desfuroylceftiofur cysteine disulfide in bovine kidney by LC–MS/MS

Shixia Feng, Chaitali Chattopadhaya, Philip Kijak, Oscar A. Chiesa, Elizabeth A. Tall, Shixia Feng, Chaitali Chattopadhaya, Philip Kijak, Oscar A Chiesa, Elizabeth A Tall

Index: J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 898 , 62-8, (2012)

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Abstract

Highlights ► We developed a new LC–MS/MS method for ceftiofur metabolite in bovine kidney. ► The new method is both determinative and confirmatory. ► The method utilizes a simple and effective extraction procedure. ► A deuterated internal standard was synthesized and used for quantitation.


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