Synthesis of pentafluorobenzoic anhydride: a superior derivatizing agent for lipids

ST Weintraub, RK Satsangi, AM Simmons…

Index: Weintraub, Susan T.; Satsangi, Rajiv K.; Simmons, Anne Marie; Williams, Robert F.; Neal Pinckard Analytical Chemistry, 1993 , vol. 65, # 17 p. 2400 - 2402

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Citation Number: 8

Abstract

The use of mass spectrometry for identification and quantitative measurement of extremely low levels of endogenous biological substances has been advanced to a significant degree by development of derivatives suitable for electron capture ionization under chemical ionization conditions. This technique, commonly termed negative ion chemical ionization (NICI), generally exhibits detection limits in the subpicogram range, thereby permitting ...