The process development of ravuconazole: an efficient multikilogram scale preparation of an antifungal agent (1)
…, D Berglund, J Bien, P Brodfuehrer…
Index: Olah, George A.; Prakash, G. K. Surya; Arvanaghi, Massoud; Bruce, Mark R. Angewandte Chemie, 1981 , vol. 93, # 1 p. 107
Full Text: HTML
Citation Number: 17
Abstract
... Volume: Page: ... This sequence also sets the second chiral center, effectively originating all stereogenic centers from methyl (R)-lactate. ... the sulfur ylide, followed by the addition of the substrate 7.(7) The adjacent chiral center induced an ∼4:1 stereoselectivity for ...
Related Articles:
2-Substituted histamines with G-protein-stimulatory activity
[Detert, H.; Hagelueken, A.; Seifert, R.; Schunack, W. European Journal of Medicinal Chemistry, 1995 , vol. 30, # 4 p. 271 - 276]