Phosphine-catalyzed annulation of thioamides and 2-alkynoates: a new synthesis of thiazolines.
Bing Liu, Roman Davis, Biren Joshi, Daniel W Reynolds
Index: J. Org. Chem. 67(13) , 4595-8, (2002)
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Abstract
The annulation of thioamides with 2-alkynoates and 2,3-dienoates under the catalysis of tri-n-butylphosphine was described. The annulation reaction provided a new entry to thiazolines, particularly those with 2-aryl substituents.
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