Tetrahedron Letters

A novel route to synthesis of flavones from salicylaldehyde and acetophenone derivatives

KV Sashidhara, M Kumar, A Kumar

Index: Sashidhara, Koneni V.; Kumar, Manoj; Kumar, Abdhesh Tetrahedron Letters, 2012 , vol. 53, # 18 p. 2355 - 2359

Full Text: HTML

Citation Number: 23

Abstract

Convenient, facile, and alternate synthesis of medicinally important flavones is reported. The 2-hydroxychalcones derived from condensation between acetophenones and salicylaldehyde, underwent oxidative cyclization on heating in the presence of catalytic iodine, generating diversified flavones under solvent-free conditions. Eleven compounds have been synthesized in good to excellent yields and their mechanism of formation is ...

Related Articles:

JSCS Vol 7 8, No. 7

[Kulkarni, Pramod S.; Kondhare, Dasharath D.; Varala, Ravi; Zubaidha, Pudukulathan K. Journal of the Serbian Chemical Society, 2013 , vol. 78, # 7 p. 909 - 916]

Microwave enhanced palladium catalysed coupling reactions: a diversity-oriented synthesis approach to functionalised flavones

[Fitzmaurice, Richard J.; Etheridge, Zac C.; Jumel, Emelie; Woolfson, Derek N.; Caddick, Stephen Chemical Communications, 2006 , # 46 p. 4814 - 4816]

Pd–carbene catalyzed carbonylation reactions of aryl iodides

[Xue, Liqin; Shi, Lijun; Han, Yuan; Xia, Chungu; Huynh, Han Vinh; Li, Fuwei Dalton Transactions, 2011 , vol. 40, # 29 p. 7632 - 7638]

One-step conversion of flavanones into isoflavones: a new facile biomimetic synthesis of isoflavones

[Tetrahedron Letters, , vol. 31, # 50 p. 7355 - 7356]

Facile synthesis of new substituted aryl and heteroarylflavones by thermal and microwave assisted Suzuki-Miyaura coupling reaction

[Joshi, Vidya; Govind Hatim, Jaywant Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2012 , vol. 51, # 7 p. 1002 - 1010]

More Articles...