[Biological activity of Penicillium sp. 10-51 exometabolites].

Ia I Savchuk, A M Zaĭchenko, E S Tsyganenko

Index: Mikrobiol. Z. 74(4) , 52-6, (2012)

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Abstract

Silica gel column chromatography (silica gel "L" II kind of activity 100/160 mkm) of the chloroform extract from the cultural filtrate of Penicillium sp. 10-51 gave two fractions (chloroform and chloroform-acetone, 5:1) having biological activity. Recrystallization yielded two compounds. On the basis of physico-chemical and spectral data these compounds were identified as curvularin and hydroxycurvularin, which have a large spectrum of biological action as to bacteria, yeast, blue-green algae and phytopathogenic micromycetes.