Inter- and intramolecular photochemical reactions of fleroxacin.
Elisa Fasani, Sandra Monti, Ilse Manet, Fedele Tilocca, Luca Pretali, Mariella Mella, Angelo Albini
Index: Org. Lett. 11(9) , 1875-8, (2009)
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Abstract
In the cation formed by photoinduced C-F bond cleavage in fleroxacin, intramolecular reaction with the N-ethyl chain is prevented by the electron-withdrawing effect of fluorine and intermolecular attack by nucleophiles is facilitated.
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