Bulletin of Experimental Biology and Medicine 2006-10-01

Effects of L-, D-, and DL-carnitine on morphometric parameters of skeletal muscle and exercise performance of laboratory animals receiving carnitine-deficient diet.

A A Spasov, I N Iezhitsa, M S Kravchenko, V B Pisarev, G L Snigur

Index: Bull. Exp. Biol. Med. 142 , 458-460, (2006)

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Abstract

Serum concentration of L-carnitine, the mean thickness of the skeletal muscle fiber, and exercise performance in the forced swimming test decreased in rats receiving a carnitine-deficient diet. Treatment with L-carnitine compensated for carnitine deficiency, while racemate and D-stereoisomer did not increase its level. L-Carnitine, but not racemate and D-stereoisomer, promoted recovery of the skeletal muscle fiber thickness and exercise performance of rats.

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