Organic Letters 2012-04-20

Application of dearomatization strategy on the synthesis of furoquinolinone and angelicin derivatives.

Yang Ye, Li Zhang, Renhua Fan

Index: Org. Lett. 14(8) , 2114-7, (2012)

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Abstract

The oxidative dearomatization of 3-(3-alkynyl-4-hydroxyphenyl)propanoic acid is combined with a cascade transition-metal catalyzed cyclization/addition/aromatization/lactamization sequence, which provides a novel approach to prepare furoquinolinone and angelicin derivatives in a convergent and efficient manner.© 2012 American Chemical Society

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