Biotechnology Letters 2005-07-01

Biotransformation of racemic diisophorone by Cephalosporium aphidicola and Neurospora crassa.

Ismail Kiran, Tamer Akar, Asli Gorgulu, Cavit Kazaz

Index: Biotechnol. Lett. 27(14) , 1007-10, (2005)

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Abstract

Racemic diisophorone (500 mg) was converted by Cephalosporium aphidicola and Neurospora crassa over 10 days at 25 degrees C to 8beta-hydroxydiisophorone in yields of 10% (52 mg) and 20% (103 mg), respectively. The structure was established by IR, specific rotation, mass spectral, 1D and 2D-NMR studies.

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