Synthesis of sydnones as potential therapeutic agents
LB Kier, D Dhawan
Index: Kier,L.B.; Dhawan,D. Journal of Pharmaceutical Sciences, 1962 , vol. 51, # 11 p. 1058 - 1061
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Citation Number: 32
Abstract
Abstract A number of new 3-alkyl sydnones have been prepared as potential therapeutic agents. A preliminary pharmacological evaluation indicated that these compounds were central nervous system stimulants. The partition coefficients between chloroform and water were determined and a correlation was found between this and the millimole dosage per kilogram in the sydnones with nonfunctional side chains. Ultraviolet and infrared data are ...
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[Greco,C.V. et al. Journal of Medicinal and Pharmaceutical Chemistry, 1962 , vol. 5, p. 861 - 865]