Catalytic properties and acidity of 1, 2-benzenedisulfonimide and some of its derivatives. An experimental and computational study

…, S Cadamuro, PG Daniele, S Dughera, G Ghigo

Index: Barbero, Margherita; Berto, Silvia; Cadamuro, Silvano; Daniele, Pier Giuseppe; Dughera, Stefano; Ghigo, Giovanni Tetrahedron, 2013 , vol. 69, # 15 p. 3212 - 3217

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Citation Number: 3

Abstract

1, 2-Benzenedisulfonimide (1) has previously been found to be an excellent and, importantly, safe Brønsted acid catalyst. In this work we present the results of a search for derivatives of 1 that are more acidic and effective. Instead of blindly synthesizing a series of analogues, we have carried out a screening process in which the pKa of 1 and a set of its derivatives were calculated. The calculated pKa values were confirmed experimentally by ...