Effect of binary combination of deltamethrin+MGK-264 on the levels of phospholipid and lipid peroxidation in the snail Lymnaea acuminata.

R N Singh, Pradeep Kumar, V K Singh, D K Singh

Index: Chemosphere 73(7) , 1032-5, (2008)

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Abstract

Effect of sublethal treatment of (40% and 60% of 48 h LC50) of deltamethrin+MGK on phospholipid level and rate of lipid peroxidation in nervous and foot tissue of Lymnaea acuminata were studied. Maximum reduction in phospholipid (24.10%) level and increase in rate of lipid peroxidation (586.8%) were observed in foot tissue of snail exposed to 60% of 48 h LC50 of deltamethrin+MGK 264 for 96 h. Alterations in the levels of phospholipids and rate of lipid peroxidation were time and concentration dependent. Use of MGK-264 with deltamethrin increases the toxicity of deltamethrin and their action on membrane phospholipids and rate of lipid peroxidation.