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MGK-264

Names

[ CAS No. ]:
113-48-4

[ Name ]:
MGK-264

[Synonym ]:
Carboximide
octacide264
Van Dyk 264
N-(2-ethylhexyl)-8,9,10-trinorborn-5-ene-2,3-dicarboximide
Pyrodone
MFCD00072467
N-(2-Ethylhexyl)-5-norbornene-2,3-dicarboximide
2-(2-ethylhexyl)-3a,4,7,7a-tetrahydro-4,7-methano-1H-isoindole-1,3(2H)-dione
n-octyl
EINECS 204-029-1
arboximide
N-Octylbicycloheptenedicarboximide
MGK 264
ENT 8,184
N-Octylbicyclo[2.2.1]hept-5-ene-2,3-dicarboximide
N-Octyl-5-norbornene-2,3-dicarboximide
(+-)-2-(2-ethyl-hexyl)-(3ac,7ac)-3a,4,7,7a-tetrahydro-4r,7c-methano-isoindole-1,3-dione
(+-)-2-(2-Aethyl-hexyl)-(3ac,7ac)-3a,4,7,7a-tetrahydro-4r,7c-methano-isoindol-1,3-dion
(3aΞ,4Ξ,7Ξ,7aΞ)-2-[(2Ξ)-2-ethylhexyl]-3a,4,7,7a-tetrahydro-4,7-methano-1H-isoindole-1,3(2H)-dione
N-(2-ethylhexyl)bicyclo[2.2.1]hept-5-ene-2,3-dicarboximide

Biological Activity

[Description]:

MgK-264 (N-octylbicycloheptenedicarboximide) is a synergist enhancing the potency of pyrethroid ingredients. MgK-264 has no intrinsic pesticidal qualities itself[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Others >> Others

[References]

[1]. Farhat Hanif, et al. Binary Combination of Carica papaya, Areca catechu and Myristica fragrans with Piperonyl Butoxide / MGK-264 against Freshwater Snail Lymnaea acuminata. Trop Life Sci Res. 2013 Dec;24(2):1-11.  

Chemical & Physical Properties

[ Density]:
1,05 g/cm3

[ Boiling Point ]:
158 °C / 2mmHg

[ Melting Point ]:
<-20ºC

[ Molecular Formula ]:
C17H25NO2

[ Molecular Weight ]:
275.38600

[ Flash Point ]:
177 °C

[ Exact Mass ]:
275.18900

[ PSA ]:
37.38000

[ LogP ]:
2.94780

[ Vapour Pressure ]:
8.35E-07mmHg at 25°C

[ Index of Refraction ]:
1.506 (20ºC)

[ Stability ]:
Stable. Incompatible with strong oxidizing agents.

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RB8575000
CHEMICAL NAME :
5-Norbornene-2,3-dicarboximide, N-(2-ethylhexyl)-
CAS REGISTRY NUMBER :
113-48-4
BEILSTEIN REFERENCE NO. :
0025024
LAST UPDATED :
199612
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C17-H25-N-O2
MOLECULAR WEIGHT :
275.43
WISWESSER LINE NOTATION :
T C555 A DVNV IUTJ E1Y4&2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C205,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
470 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
30ZDA9 "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971 Volume(issue)/page/year: -,139,1971
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
YKYUA6 Yakkyoku. Pharmacy. (Nanzando, 4-1-11, Yushima, Bunkyo-ku, Tokyo, Japan) V.1- 1950- Volume(issue)/page/year: 32,605,1981
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
470 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
SPEADM Special Publication of the Entomological Society of America. (4603 Calvert Rd., College Park, MD 20740) Volume(issue)/page/year: 78-1,5,1978 ** REPRODUCTIVE DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
346 mg/kg
SEX/DURATION :
multigenerations
TOXIC EFFECTS :
Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated) Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 9,555,1966 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1968 No. of Facilities: 34 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 1066 (estimated) No. of Female Employees: 587 (estimated)

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H311

[ Precautionary Statements ]:
P280-P312

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R21

[ Safety Phrases ]:
S26-S36/37/39-S36/37

[ RIDADR ]:
UN 2810

[ RTECS ]:
RB8575000

[ HS Code ]:
2925190090

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2925190090

[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Effects of synergists on bendiocarb and pyrethrins resistance in the German cockroach (Dictyoptera: Blattellidae).

J. Econ. Entomol. 80(4) , 728-32, (1987)

Effect of binary combination of some plant-derived molluscicides with MGK-264 or piperonyl butoxide on the reproduction of the snail Lymnaea acuminata.

Pest Manag. Sci. 61(2) , 204-8, (2005)

The effects of sub-lethal treatments (20 and 60% of 24-h LC(50)) with plant-derived molluscicides Annona squamosa, acetogenins, Argemone mexicana seed and protopine, in combination (1 + 5) with MGK-26...

Isocratic reversed-phase liquid chromatographic method for the simultaneous determination of (S)-methoprene, MGK264, piperonyl butoxide, sumithrin and permethrin in pesticide formulation.

J. Chromatogr. A. 983(1-2) , 145-52, (2003)

An isocratic reversed-phase high-performance liquid chromatographic (RP-HPLC) method development for the simultaneous determination of five active ingredients (S)-methoprene, MGK264, PBO, sumithrin an...


More Articles


Related Compounds

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