Mutagenesis 1986-07-01

Computer-automated prediction of the mutagenicity of benzidine, 4,4"-diaminoterphenyl, 4-dimethylaminoazobenzene and 4-cyanodimethylaniline: comparison with the results of the Second UKEMS Collaborative Study.

H S Rosenkranz, M R Frierson, G Klopman

Index: Mutagenesis 1(4) , 275-82, (1986)

Full Text: HTML

Abstract

There was agreement between the experimental results, obtained in the course of the Second UKEMS Collaborative Study, for the mutagenicity in Salmonella typhimurium of benzidine, 4,4"-diaminoterphenyl, 4-dimethylaminoazobenzene and 4-cyanodimethylaniline and the mutagenicity predicted by CASE (Computer Automated Structure Evaluation), a recently developed artificial intelligence system.

Related Compounds

Related Articles:

Predicting the carcinogenicity of the aromatic amine derivatives tested in the second UKEMS Collaborative Study.

1986-03-01

[Mutagenesis 1(2) , 119-23, (1986)]

The formation of a novel mercapturic acid during the metabolism of an N-methyl aromatic amine, 4-cyano-N,N-dimethylaniline.

1984-07-15

[Biochem. Pharmacol. 33(14) , 2345-6, (1984)]

The fate of 4-cyano-N,N-dimethylaniline in rats; a novel involvement of glutathione in the metabolism of anilines.

1984-12-01

[Xenobiotica 14(12) , 925-34, (1984)]

Presence and absence of excited state intramolecular charge transfer with the six isomers of dicyano-N,N-dimethylaniline and dicyano-(N-methyl-N-isopropyl)aniline.

2011-10-13

[J. Phys. Chem. A 115(40) , 10823-45, (2011)]

NMR study of whole rat bile: the biliary excretion of 4-cyano-N,N-dimethyl aniline by an isolated perfused rat liver and a liver in situ.

1995-05-01

[J. Pharm. Biomed. Anal. 13(6) , 735-45, (1995)]

More Articles...