Group IV-Metal-Catalyzed Aminolysis of N-Acyl-2-oxazolidinones: Applications to the Chemoselective and Enantioselective Carbonylation of Primary Alkylamines

T Yokomatsu, A Arakawa…

Index: Yokomatsu, Tsutomu; Arakawa, Akio; Shibuya, Shiroshi Journal of Organic Chemistry, 1994 , vol. 59, # 12 p. 3506 - 3508

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Citation Number: 31

Abstract

Reversible acyl transfer reactions catalyzed by enzymes such as lipase in organic solvent have great practical utility, in addition to being of theoretical interest, in asymmetric synthesis due to their facile chiral Such acyl transfer processes are also of practical utility in chemoselective acylation of polyheterofunctional compounds. These enzymatic reactions are recognized to proceed through acyl-enzyme complex 1, the enzyme moiety of which ...

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