Journal of the American Chemical Society
2011-09-28
Concise total synthesis and stereochemical revision of (+)-naseseazines A and B: regioselective arylative dimerization of diketopiperazine alkaloids.
Justin Kim, Mohammad Movassaghi
Index: J. Am. Chem. Soc. 133 , 14940-14943, (2011)
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Abstract
Concise and enantioselective total syntheses of (+)-naseseazines A and B are described. Our regioselective and directed dimerization of diketopiperazines provides their critical C3-C(sp(2)) linkages, an assembly with plausible biogenetic relevance. We revise the absolute stereochemistry of (+)-naseseazines A and B.
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