Food and Chemical Toxicology 2012-06-01

Comparison of growth, serum biochemistries and n−6 fatty acid metabolism in rats fed diets supplemented with high-gamma-linolenic acid safflower oil or borage oil for 90 days

Patrick Tso, Jody Caldwell, Dana Lee, Gregory P. Boivin, Stephen J. DeMichele

Index: Food Chem. Toxicol. 50(6) , 1911-9, (2012)

Full Text: HTML

Abstract

Highlights ► Feeding diets containing HGSO or borage oil for 90days had similar biologic effects. ► Metabolism of primary n−6 fatty acids in plasma and organ phospholipids was similar. ► No adverse effects were observed with HGSO fed at 1980mg/kg bw/day and 2530mg/kg bw/day. ► HGSO is biologically equivalent to borage oil, providing a safe alternative source of GLA in the diet.

Related Compounds

Related Articles:

Dietary linoleic acid and α-linolenic acid differentially affect renal oxylipins and phospholipid fatty acids in diet-induced obese rats.

2013-09-01

[J. Nutr. 143(9) , 1421-31, (2013)]

Lymphatic diamine oxidase secretion stimulated by fat absorption is linked with histamine release.

2013-04-15

[Am. J. Physiol. Gastrointest. Liver Physiol. 304(8) , G732-40, (2013)]

Effects of dietary fat energy restriction and fish oil feeding on hepatic metabolic abnormalities and insulin resistance in KK mice with high-fat diet-induced obesity.

2013-01-01

[J. Nutr. Biochem. 24(1) , 267-73, (2013)]

Effect of safflower oil on the protective properties of the in situ formed salivary pellicle.

2012-01-01

[Caries Res. 46(5) , 496-506, (2012)]

Menhaden oil, but not safflower or soybean oil, aids in restoring the polyunsaturated fatty acid profile in the novel delta-6-desaturase null mouse.

2012-01-01

[Lipids Health Dis. 11 , 60, (2012)]

More Articles...