Transformation of 2-aminoacetophenone to ( S) -2-amino-1-phenylethanol by Arthrobacter sulfureus.

Guogang Zhao, Jianjun Wang, Kai Ma, Liu Yang, Sheng Wu, Yanbin Liu, Wanru Sun

Index: Biotechnol. Lett. 26(16) , 1255-9, (2004)

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Abstract

A new isolate of Arthrobacter sulfureus , when incubated at 50 g resting cells (dry cell wt) l(-1) with 50 g glucose l(-1) and 1 g 2-aminoacetophenone l(-1) in 50 mm potassium buffer (pH 7, 4 ml) at 30 degrees C, produced ( S )-2-amino-1-phenylethanol (e.e. >99%) with 75% yield in 6 h.