Structural investigation of biologically active phenolic compounds isolated from European tree species.

Izabela Redzynia, Natasza E Ziółkowska, Wiesław R Majzner, Stefan Willför, Rainer Sjöholm, Patrik Eklund, Grzegorz D Bujacz

Index: Molecules 14(10) , 4147-58, (2009)

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Abstract

X-ray structures of two compounds isolated from wood knots of coniferous trees, namely dihydrokaempferol (3,5,8,13-tetrahydroxyflavanon) and lariciresinol (3,14-dimetoxy-7,10-epoxylignan-4,15,19-triol), are presented here. Diffraction data for the Dihydrokaempferol crystals were collected on a CAD4 diffractometer and on a synchrotron for the lariciresinol crystal. The investigated compounds inhibit lipid peroxidation and lariciresinol is additionally a good scavenger of superoxide radicals. The structural data presented in this work provide a useful basis for designing more active compounds with potential use as antioxidants.