Heterocycles

A facile one-pot synthesis of 4-alkoxy-1, 3-benzenedicarbonitrile

M Hasegawa

Index: Heterocycles, , vol. 47, # 2 p. 857 - 864

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Citation Number: 22

Abstract

... Abstract. 2-(3-Cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxlic acid (TEI-6720) was prepared. The introduction of cyano group to 4-nitrobenzonitrile with KCN in dry DMSO followed by quenching with alkyl halide afforded ...