Syntheses of isoflavones and isoflavone glycosides, and their inhibitory activity against bovine liver β-galactosidase
…, I Deguchi, N Sugiyama, S Kamiya
Index: Nishiyama, Kiyotoshi; Esaki, Sachiko; Deguchi, Ikuko; Sugiyama, Naoko; Kamiya, Shintaro Bioscience, Biotechnology, and Biochemistry, 1993 , vol. 57, # 1 p. 107 - 114
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Citation Number: 10
Abstract
To clarify the relationship between the structure and inhibitory action toward β-d- galactosidase (EC 3.2. 1.21) of isoflavones and isoflavone glycosides, a number of polyhydroxyisoflavones, and the α-l-rhamnosides and β-l-quinovosides of daidzein and genistein were synthesized. Among the polyhydroxyisoflavones, 2′, 3′, 4′, 7- tetrahydroxyisoflavone showed the strongest inhibitory activity (K i= 26× 10-6 m). Among ...
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