Bioorganic & Medicinal Chemistry 2011-01-01

N4-[Alkyl-(hydroxyphosphono)phosphonate]-cytidine—New drugs covalently linking antimetabolites (5-FdU, araU or AZT) with bone-targeting bisphosphonates (alendronate or pamidronate)

Herbert Schott, Daniel Goltz, Timm C. Schott, Claudia Jauch, Reto A. Schwendener, Herbert Schott, Daniel Goltz, Timm C. Schott, Claudia Jauch, Reto A. Schwendener

Index: Bioorg. Med. Chem. 19(11) , 3520-6, (2011)

Full Text: HTML

Abstract

New cytostatic antimetabolite-bisphosphonates.


Related Compounds

Related Articles:

Development of an LC-MS/MS assay for the quantitative determination of the intracellular 5-fluorouracil nucleotides responsible for the anticancer effect of 5-fluorouracil.

2015-06-10

[J. Pharm. Biomed. Anal. 110 , 58-66, (2015)]

Evidence for Transcriptional Activity in the Syncytiotrophoblast of the Human Placenta

2009-04-01

[Placenta 30(4) , 329-34, (2009)]

Plastid uridine salvage activity is required for photoassimilate allocation and partitioning in Arabidopsis.

2011-08-01

[Plant Cell 23(8) , 2991-3006, (2011)]

TDP-43 localizes in mRNA transcription and processing sites in mammalian neurons.

2009-09-01

[J. Struct. Biol. 167(3) , 235-41, (2009)]

The products of 5-fluorouridine by the action of the pseudouridine synthase TruB disfavor one mechanism and suggest another.

2011-08-10

[J. Am. Chem. Soc. 133(31) , 11826-9, (2011)]

More Articles...